Combined microfluidic-optical DNA analysis with single-base-pair sizing capability
نویسندگان
چکیده
منابع مشابه
Combined microfluidic-optical DNA analysis with single-base-pair sizing capability.
DNA sequencing by microchip capillary electrophoresis (CE) enables cheap, high-speed analysis of low reagent volumes. One of its potential applications is the identification of genomic deletions or insertions associated with genetic illnesses. Detecting single base-pair insertions or deletions from DNA fragments in the diagnostically relevant size range of 150-1000 base-pairs requires a varianc...
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ژورنال
عنوان ژورنال: Biomedical Optics Express
سال: 2016
ISSN: 2156-7085,2156-7085
DOI: 10.1364/boe.7.005201